Publications

For the most current publications, visit PubMed.

  • Sarfraz, N. & Braselmann, E.# (2023), It’s complicated: the interplay of Kif1c mRNA localization in cell protrusions, assembly of protein binding partners on the KIF1C protein, and cell migration, Genes & Dev., 37:1-3.

  • Sarfraz, N., Moscoso, E., Oertel, T., Lee, H. J., Ranjit, S., Braselmann, E.# (2023), Visualizing orthogonal RNAs simultaneously in live mammalian cells by fluorescence lifetime imaging microscopy (FLIM), Nat. Comm., 14:867.

Before Georgetown appointment:

  • Braselmann E.#, Stasevich T.J., Lyon K., Batey R.T., Palmer A.E.# (2019), Detection and quantification of single mRNA dynamics with the Riboglow fluorescent RNA tag, in revision, bioRxiv pre-print: https://doi.org/10.1101/701649 (#co-corresponding authors).

  • Braselmann E., Rathbun C.M., Richards E.M., Palmer A.E. (2020), Illuminating RNA biology: Tools for imaging RNA in live mammalian cells, Cell Chem. Biol., 27(8), 891-903.

  • Braselmann E., Palmer A.E. (2020) A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells, Methods Enzymol., 641, 343-372.

  • Braselmann E., Wierzba A.J.*, Polaski J.T.*, Chromiński M., Holmes Z. E., Hung S.-T., Batan D., Wheeler J. R., Parker R., Jimenez R., Gryko D., Batey R.T., Palmer A.E. (2018), A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells, Nat. Chem. Biol., 14 (10), 964-971 (*equal contributions for A.J. Wierzba & J.T. Polaski).

  • Batan D.*, Braselmann E.*, Minson M., Nguyen D.M.T., Cossart P., Palmer A.E. (2018), A Multicolor Split-Fluorescent Protein Approach to Visualize Listeria Protein Secretion in Infection, Biophys. J., 115 (2), 251-62 (*equal contributions).

  • Specht E.A., Braselmann E., Palmer A.E. (2017) A Critical and Comparative Review of Fluorescent Tools for Live Cell Imaging, Annu. Rev. Physiol., 79, 93-117.

  • Qin, Y., Sammond, D.W., Braselmann, E., Carpenter, M.C., Palmer, A.E. (2016) Development of an Optical Zn2+-Probe Based on a Single Fluorescent Protein, ACS Chem. Biol., 11 (10), 2744-51.

  • Braselmann E.*, Chaney J.L., Champion, M.M., Clark P.L. (2016) The DegP Chaperone Suppresses Toxic Inner Membrane Translocation Intermediates, PloS One, 11 (9), e0162922 (*corresponding author).

  • Cressiot B., Braselmann E., Oukhaled A., Elcock A.H., Pelta J.,Clark P.L. (2015) Dynamics and Energy Contributions for Transport of Unfolded Pertactin through a Protein Nanopore, ACS Nano, 9 (9), 9050-61.

  • Drobnak I., Braselmann E. & Clark P.L. (2015) Multiple driving forces required for efficient secretion of autotransporter virulence proteins, J. Biol. Chem., 290 (16), 10104-16.

  • Drobnak I., Braselmann E., Chaney J.L., Leyton D.L., Bernstein H.D., Lithgow T., Luirink J., Nataro J.P. & Clark P.L. (2015) Of linkers and autochaperones: an unambiguous nomenclature to identify common and uncommon themes for autotransporter secretion, Mol. Microbiol., 95 (1), 1-16, MicroReview.

  • Braselmann E., Chaney J.L. & Clark P.L. (2013) Folding the Proteome. Trends Biochem. Sci., 38 (7), 337-44.  Featured on the cover. 

  • Braselmann E. & Clark P.L. (2012) Autotransporters:  the Cellular Environment Reshapes a Folding Mechanism to Promote Protein Transport, J. Phys. Chem. Lett., 3 (8), 1063-71. Featured on the cover and as a video on the journal website.

  • Renn J.P., Junker M., Besingi R.N., Braselmann E., Clark P.L. (2012); ATP-independent control of autotransporter virulence protein transport via the folding properties of the secreted protein, Chem. Biol. 19 (2), 287-96. Featured on the cover.

Patents

US 2020/0149046A1
Compositions and Methods for Tagging Ribonucleic Acids

This invention relates to the field of ribonucleic acid (RNA) regulation of intracellular activity. In particular, the invention relates to compositions and methods of identifying and tracking specific intracellular RNAs. For example, a fluorescently tagged RNA probe may be tracked by in vivo live imaging throughout its intracellular lifetime in order to determine its purpose and identify regulatory targets to modify its effects. Alternatively, an RNA probe may carry a therapeutic payload for treatment of medical condition or disorder.

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